LL-37

Overview

LL-37 is a cationic antimicrobial peptide belonging to the cathelicidin family, composed of 37 amino acids and derived from the human CAP18 protein precursor. It is studied exclusively under controlled laboratory and preclinical conditions for its potential roles in innate immune response, cellular signaling, and host defense mechanisms. Research investigates how LL-37 interacts with cell membranes, modulates cytokine pathways, and contributes to cellular barrier stability within in vitro and non-human models.

Specifications

• Unit Size: 10 mg per vial

• Form: Lyophilized powder

• Storage: Store dry at 2 °C–8 °C. After reconstitution, refrigerate at 2 °C–8 °C and use within 10–14 days.

• Documentation: Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) available upon request.

Research Context

In vitro and preclinical models have examined LL-37 in relation to:

• Modulation of innate immune signaling and antimicrobial peptide pathways

• Interaction with bacterial and viral membrane structures in controlled assays

• Influence on cytokine expression and inflammatory response mechanisms

• Studies of epithelial defense, wound model responses, and peptide-induced cell signaling

All findings are derived from laboratory research and are not indicative of safety, efficacy, or function in humans or animals.

Intended Use / Restrictions

• For laboratory research use only

• Not for human or veterinary use

• Not a drug, dietary supplement, or medical device

• Buyer must be a qualified researcher or institution and assumes all responsibility for lawful handling and compliance with applicable safety standards and regulations.

Important Notice

The information provided is intended solely for scientific and educational purposes. The seller makes no representations or claims regarding safety, efficacy, or suitability for clinical use. This material is not intended to diagnose, treat, prevent, or cure any disease. Proper storage, handling, and disposal are required under institutional biosafety protocols.